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Cell therapy for autoimmune and rheumatological diseases

Cell therapy for autoimmune and rheumatological diseases

Systemic autoimmune and rheumatic diseases are chronic, progressive pathologies. They arise due to a malfunction of the immune system. As a result of the malfunction, the body begins to perceive its own tissues and organs as foreign and triggers an autoimmune process, which leads to inflammation, damage, and loss of function.

The service is available in branches:
  • Odessa, Sudnobudivna, 1B
  • Kyiv, Kostiantynivska, 57
Cell therapy for autoimmune and rheumatological diseases

Such diseases are usually difficult to treat, but the VIRTUS Institute, together with the biotechnology laboratory SmartCell, have developed innovative approaches to achieve maximum results – AutoImmuneCELLNESS® and RheumaCELLNESS®.

Common autoimmune and rheumatic diseases

Systemic autoimmune and rheumatic diseases negatively affect the functioning of all organs and systems. In fact, the whole body suffers from them: from the cardiovascular system, the risk of myocarditis, vasculitis, pericarditis increases, the functions of the liver, endocrine, digestive systems are disrupted, renal or respiratory failure develops. The list of common autoimmune diseases includes:

  • systemic lupus erythematosus (SLE) (chronic connective tissue disease);
  • autoimmune thyroiditis (Hashimoto’s);
  • celiac disease (intestinal dysfunction accompanied by gluten intolerance);
  • systemic scleroderma;
  • myasthenia gravis;
  • vasculitis.

Rheumatoid arthritis and psoriatic arthritis are both autoimmune and rheumatic in nature, therefore they require a comprehensive approach. Other common rheumatological diseases:

  • osteoarthritis;
  • gout;
  • ankylosing spondylitis;
  • pseudogout;
  • Sjögren’s syndrome;
  • rheumatic diseases of soft tissues (fibromyalgia).

Autoimmune diseases are statistically more common in women. It is not just pain or fatigue – it is a systemic, multi-level lesion that can lead to disability and life-threatening. However, there are modern methods of treatment, in particular with stem cells, which can significantly improve the condition of patients with autoimmune diseases. Stem cell treatment in Ukraine is available to patients, in particular at the VIRTUS Institute.

Indications for cell therapy in autoimmune and rheumatological diseases

The indication for cell therapy is the very presence of an autoimmune or rheumatological disease, especially if other types of treatment have not led to a positive result. As a rule, patients with autoimmune or rheumatological diseases present with the following complaints:

  • pain in the joints, muscles, skin;
  • stiffness, joint deformation, change in the shape of the limbs;
  • cold limbs, change in the color of the fingers (Raynaud’s disease);
  • rashes, seals, ulcers on the skin;
  • weakness, fatigue, fever;
  • shortness of breath, palpitations, chest pain;
  • impaired functioning of the kidneys, liver, lungs, intestines.

For example, Raynaud’s syndrome is one of the first signs of the initial stage of scleroderma, along with redness and swelling of individual areas of the skin. Timely selected cell therapy allows not only to slow down the development of scleroderma, but also to treat its consequences, including on the face.

Benefits of cell therapy for autoimmune and rheumatic diseases

Since autoimmune diseases negatively affect all organs and systems, we offer patients a comprehensive approach to properly prepare the body for the introduction of stem cells and obtain an optimal result. Cell therapy reduces the risk of disability and improves the quality of life, returning patients to activity, confidence and health.

The principle of action of cell therapy for autoimmune and rheumatic diseases

Stem cells are unique in that they have the ability to transform into cells of other types, divide and thus restore various organs. Thus, cell therapy acts as follows:

  • modulates the immune system, reducing autoimmune aggression;
  • reduces inflammation, alleviating symptoms;
  • regenerates damaged tissues – blood vessels, skin, joints, internal organs;
  • improves blood supply, which is important for Raynaud’s disease and vasculitis.

Scleroderma and other autoimmune diseases cannot be completely cured, but thanks to cell therapy, the disease can be put into remission, reducing the frequency of medication and reducing the frequency of exacerbations.

Results of cell therapy in autoimmune and rheumatic diseases

Currently, cell therapy is considered one of the most promising areas of treatment for autoimmune and rheumatic diseases. It helps to significantly reduce symptoms and slow down the development of the disease. Patients experience the following results of cell therapy:

  • reduction of pain, stiffness, improvement of mobility in the treatment of polyarthritis and other joint diseases;
  • restoration of blood supply to the extremities, relief of symptoms of Raynaud’s disease;
  • disappearance of skin manifestations (indication, rashes);
  • improvement of well-being, increased energy;
  • reduction in the frequency of exacerbations and the need for high doses of drugs;

All this leads to an overall improvement in the quality of life.

Popular questions

How to relieve exacerbation of rheumatoid arthritis?

The use of cell therapy in exacerbation of rheumatoid arthritis is quite appropriate. A comprehensive approach includes preparation for the introduction of cells by the method of blood purification by plasmapheresis. In this way, excess immune complexes are removed and the body’s autoimmune reaction is reduced. This creates a better background for the work of stem cells to restore the joint.

How do people die from rheumatoid arthritis?

People die not from rheumatoid arthritis itself, but from its complications, mostly from the cardiovascular system. The consequence of rheumatoid arthritis is disability: immobility, which can be accompanied by injuries to the musculoskeletal system. Such patients are often bedridden or forced to undergo operations that carry health risks.

What is stem cell rejuvenation?

Stem cells not only help treat autoimmune and rheumatological diseases, but also fight age-related changes. For example, we use injections of our own fibroblasts (connective tissue cells responsible for the production of collagen and elastin) to restore skin density and elasticity, as well as improve the quality and color of the complexion.

Preparation for stem cell treatment for autoimmune and rheumatological diseases

Before starting treatment, the patient undergoes mandatory tests: clinical and biochemical blood, HIV and hepatitis tests, as well as a screening test for oncopathology. Rheumatoid factor can be elevated not only in rheumatoid arthritis, but also in other inflammatory diseases, so it is not sufficient in itself to establish a diagnosis.

Stages of cell therapy for autoimmune and rheumatological diseases

Complex treatment of autoimmune and rheumatological diseases also includes plasmapheresis procedures – an extracorporeal method of blood purification through a device that allows pathogens, autoimmune antibodies and other harmful substances that cause chronic diseases to be removed from it. So, the stages of cell therapy at the VIRTUS Institute are as follows:

  1. Primary diagnostics, determination of disease activity.
  2. Consultation with Smart Cell cell therapy specialists.
  3. Consultation with a plasmapheresis doctor to determine the indications and contraindications for the procedure, as well as the number of sessions.
  4. Collection and preparation of own or donor mesenchymal stem cells (MSCs).
  5. Conducting plasmapheresis sessions.
  6. AutoImmuneCELLNESS® — intravenous administration for a systemic effect.
  7. RheumaCELLNESS® comprehensive approach — local administration to the joints, skin and systemic administration of the cell preparation to enhance the result.

Before the treatment of rheumatoid arthritis, AMC therapy can be performed, which helps restore trophism and blood supply to the affected joint and create better conditions for the action of stem cells.

Rehabilitation after cell therapy for autoimmune and rheumatological diseases

The doctor provides recommendations for rehabilitation after cell therapy for autoimmune and rheumatological diseases individually for each patient. They depend on the state of health and the body’s response to the administration of stem cells.

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